Lutheran Medical Center
Date: 02/26/2010
Article title: Oral Soft Tissue Manifestations and CD4 Lymphocyte Coutns in HIV-infected Children
Author(s):Howell, Jandinski, Palumbo, SHey, Houpt
Journal: Pediatric Dentistry
Volume (number): 18:2
Month, Year: 1996
Major topic: HIV related oral manifestations in children.
Minor topics: Realtionship of CD4 lymphocyte levels to the presence of oral soft tissue lesions.
Type of Article: Clinical Investigation
Main Purpose: Investigate the prevalence of oral soft tissue lesions associated with HIV
Overview of method of research: 60 HIV infected children received comprehensive oral examinations. Candida, pseudomembranous and erythematous were grouped with angular cheilitis; Herpes was diagnosed by clinical response to Acyclovir. Modified gingival probings were done. Perio disease diagnosis was based on it’s level of aggression--yikes.
CD4 counts were obtained within 3 months of the oral exams and adjusted for patient age.
Findings:
Even well managed children with HIV often have significant oral disease, Gingivitis in HIV children is associated with (guess what?!) poor oral hygiene, and soft tissue lesions were associated with low CD4 counts.
Key points/Summary :
Because so many HIV pts have oral disease, its presence could be used a a diagnosis factor. Linear gingival erythema was found in 38% of the kids and it is a known manifestation of HIV in adults--that and mustaches.
Children experience less HIV associated periodontitis.
Assessment of article:
This kind of seems like common sense at this point, but it was a good article. Also this study was done 20 years ago (published 5 years later) and our knowledge of HIV has really increased since then.
No comments:
Post a Comment