gingival disease

Resident’s Name: Joanne Lewis Date: April 16, 2010

Article title: Dental Plaque-Induced Gingival Diseases

Author(s): Angelo Maricotti

Journal: Ann Periodontol

Volume (number): 4(1)

Month, Year: 1999

Major topic: gingivitis

Type of Article: review

Main Purpose: to define and classify gingivitis

Key points/Summary: The characteristics common to all gingival diseases are: signs and symptoms that are confined to the gingival, the presence of dental plaque to initiate and exacerbate the severity, clinical signs of inflammation, no attachment loss, reversibility by removing the etiology, and possible role as a precursor to attachment loss. 2 categories of plaque-induced gingival diseases are: those affected by local factors and those affected by local factors and modified by systemic factors. Systemic factors include systemic disease (diabetes mellitus, leukemia), malnutrition (scurvy), hormone fluctuations, or drugs.

Assessment of article: Basic information.

Drug Induced gingival overgrowth

Review by Kris Hendricks

(sorry it's board time--time to study articles, not write about them)

authors: Dongari, McDonnell, Langlais

Published in Oral Surgery, Oral Medicine, Oral Pathology in October 1993

The point:

Certain Anticonvulsants, Cyclosporine, and other calcium channel blockers have been shown to produce gingival enlargement in susceptible patients.

The pharmacologic mechanism seems to be similar at the cellular level, but these drugs act on different target tissues.

The hyperplastic response is not well understood, but it could be from an alteration in collagen metabolism and other host cell response mechanisms.

Treatment:

Until science can provide more insight into this, treatment should consists of plaque control, professional debridement and resective gingival procedures.

My take:

There seem to have been several board questions over the years that have emphasized drug induced gingival enlargement.