Growth Hormone Deficiency

Resident’s Name: Derek Banks Date: May 29, 2009
Article title: Growth Hormone Deficiency
Author(s):
Journal: Pediatric Medicine Textbook
Volume (number): Page 811-814
Month, Year:
Major topic: Metabolic Disorders
Minor topic(s): Growth Hormone Deficiency
Type of Article: Textbook
Main Purpose: Discuss the implications of growth hormone deficiency
Epidemiology: Sometimes idiopathic, other times a genetic link can be found – thought to be autosomal recessive. GH deficiency is 4x more common in boys than girls, and may be linked to abnormal deliveries or history of perinatal asphyxia. Patients with GH deficiency usually appear normal at birth with appropriate weight and length. Impairment of linear growth first manifests itself in the first or second year of life. Growth of the facial bones is slowed, making size discrepancy between face and calvaria. Dental development delays can occur as well. Obesity is common among these patients.
Diagnosis: Diagnosis is based on basis of growth data. Also, serial blood draws may reveal abnormal production of Growth/other hormones at different times throughout the night. A number of chemical/metabolic stimuli exist that can elicit a release of growth hormone.
Treatment: Ask Manny, Arnold, or Lance…..
Assessment of article: Good summary.