Showing posts with label 03/05/2010. Show all posts
Showing posts with label 03/05/2010. Show all posts

Friday, March 5, 2010

EB - two case reports

Resident’s Name: Joanne Lewis Date: March 5, 2010

Article title: Epidermolysis bullosa: dental and anesthetic management of two cases

Author(s): J. Tim Wright, DDS, MS

Journal: Oral Surgery, February 1984, Volume 57, Number 2

Type of Article: case report

Main Purpose: to present the dental and anesthetic management of two severely affected EB patients.

Overview: Two siblings were diagnosed as having recessive epidermolysis bullosa atrophicans-gravis Herlitz; severe enamel hypoplasia with typical cutaneous, esophageal, and ocular lesions was seen in both cases. Both children required dental rehabilitation under general anesthesia. Special care was taken in the surgical management of the cases to prevent nosocomial infections or minor tissue trauma that might precipitate the formation of bullae. The special precautions were:

- synthetic sheepskin bedding was used on all carts, beds, and the operating table.

- patient’s arm was wrapped in guaze before placement of the blood pressure cuff.

- orotracheal intubation was used; the tubing, laryngoscope blade, and perioral area was lubricated with 1%hydrocortisone cream.

- moist guaze packs were place on one side of the orotracheal tube.

- prior to extubation, the anesthesiologist used an endoscope to check for bullae.

Dental treatment consisted of stainless steel crown and extractions.

Key points/Summary: Patients with EB often require early and extensive dental treatment – this dental treatment is most safely accomplished in the operating room using special precautions.

Assessment of article: interesting.

Thursday, March 4, 2010

Use of endosseous implants in a 3-year-old child with ectodermal dysplasia: case report and 5-year follow up

Resident: J. Hencler
Date: 03/05/2010

Article title:
Use of endosseous implants in a 3-year-old child with ectodermal dysplasia: case report and 5-year follow up

Author(s): Albert D. Guckes, DDS, MSD George R. McCarthy, DDS Jaime Brahim, DDS, MS
Journal: Pediatric Dentistry-19: 4, 1997
Major topic: Ectodermal dysplasia
Type of Article: Case Report

Main Purpose:
Present a case report of implant placement in a 3yo w/ ectodermal dysplasia, subsequent prostho tx, and 5 yr follow-up.

Background:
Ectodermal dysplasia represents a grp of inherited disorders characterized by defects in tissue that are derived from ectoderm.

Case:
3 yo white male dx w/ Christ-Siemens-Touraine ectodermal dysplasia. 4 mandibular and 2 maxillary implants were placed (stage 1 complete). Max/Mand bone augmentation with hydroxyapatite (HA) was completed. Clinical exam was consistent w/ dx of hypohidrotic ecto dysplasia. 2 max tooth buds observed. Implants healed normal, child scheduled for stage 2 uncovering of implants and placement of mand healing abutments. Maxillary right implant was removed due to mobility. Max left implant was covered b/c it alone could not contribute to prosthesis support. Max conventional complete denture and mand over-denture were fabricated and adjusted/remade over 5 yrs as needed to accommodate eruption of 2 max teeth and overall growth.

Follow-up:
Mand implants in function 4 yrs. Relative position w/in ant mand unchanged as growth occurs in the rami and condyles. Some resorption of HA noted radiographically after 5 yrs. Relative position of unloaded single max implant has not moved w/ the downward and forward growth of the maxilla but is positioned in close proximity to the nasal floor. This implant will require close monitoring, as the ultimate position is uncertain.

Key points in the article discussion:
This case confirms that implants placed int the ant mand wil move w/ the mand as growth occurs in the condyles and rami. Mand rotation that occurs w/ growth has not caused problems relative to implant angulation and prosthetic occl plane. The change in implant position of the max implant as the mand grows downward is not unexpected and may be a significant complication and may require removal. While the magnitude of the change in position of the max implant may not be typical, it provides a cautionary note regaeding implant placement in the growing maxilla. The most important issue raised by this case is if and when tx of a young child w/ implants is indicated and prudent. There is little research identifying any physiologic benefits of placing implants in children. The theoretical possibility exists that significant edentulism in a growing child adversely affects craniofacial growth. While the lit supports the concept that craniofacial devel is adversely affects in ecto dyplasia children, the exact mechanism by which the growth is affected is unclear. The most obvious effect of ecto dyplasia is lack of alveolar bone in areas of anodontia. At present there is no evidence from clinical trials to indicate that implant placement in young children has a positive effect on craniofacial growth and devel.

Summary of conclusions:
This case provides a good opportunity to follow the consequences of placing oral implants in a very young patient. Psychological benefits may be associated w/ using implant to support an oral prosthesis in the mandible of a teenage child with many missing teeth. However, clinical research has not demonstrated compelling reasons to place implants in pre-teenage children.

Assessment of article:
Very interesting article. Implant placement in the growing child will require multi-specialty extensive tx planning. I feel that ultimately it should be the parent’s decision once they are fully informed of prognosis and tx requirements including ongoing maintenance to accommodate for future growth.

Ehlers Danlos (Great Video)

Since my article was forthcoming I decided to post this super sweet video about my topic instead. We may not have time to watch it all, but we should at least watch a few minutes.

Ectodermal Dysplasia

Resident: Adam J. Bottrill
Date: 05MAR10
Region: Providence
Article title: Ectodermal Dysplasia
Author(s): Wright, T. et al
Journal: ?
Page #s: pp. 17211724
Year: ?
Major topic: Ectodermal Dysplasia
Minor topic(s): N/A
Type of Article: Topic Summary

Main Purpose: Describe the different clinical characteristics of Ectodermal Dysplasia (ED)
Overview of method of research: Summary

Key points in the article discussion:
A. General
1. Includes all conditions having a developmental defect that embryologically affects the ectoderm.
2. Over 120 conditions classifiable as ED’s.
3. More recent definitions of ED include any one of the following: hypotrichosis, hypodontia, onychodysplasia, anhydrosis … PLUS ectodermal involvement.
4. Most types remain a purely clinical diagnosis… not yet molecularly characterized.
5. Other non-ectoderm structures may be involved: limbs, bones, palate, neuro, organs, repro.
6. Hair 90%, skin 85%, teeth 80%, nails 75%, face 72%
7. No FH, and often hard to diagnose… VERY few are localized to specific DNA and inheritance.
a. female carriers often have tooth involvement.
8. Most treatment is only preventative or palliative… there is no cure.
9. Dental implants are often treatment of choice as early as during teenage yrs.






























Assessment of article:
Keep it simple stupid.